Proxmox
Proxmox Virtual Environment is a complete open-source platform for enterprise virtualization with a built-in web interface to easily manage VMs and containers. The cornerstone of my homelab, most of my containers/services/websites will run on Proxmox except where it makes sense to have a separate server for hardware-specific purposes. (Examples: TrueNAS is just better running on bare metal; Jellyfin needs to run on hardware that has Intel Quick Sync for optimal video transcoding.)